In normal conditions, the body E. coli do not cause disease. But to cause disease in immunocompromised. Or debilitating condition called opportunistic infections. It is the major cause of infections in hospitals in addition to those mentioned above. Groups who are at risk of infection is important. Those who have work-related diseases. Causing an infection from the operation include healthcare workers in contact with infected patients. And those who work in medical laboratories, which are exposed to body fluids from an infected person and so on.