The silks produced by silkworms and spiders have fibrous proteins that may have several
Conformations. Silks can be processed into many forms suitable for a variety of biomedical and
tissue engineering applications. They can be modified by chemical treatment or used in
combination with other materials in order to vary mechanical properties and surface chemistry.
By these means, biomaterials appropriate to specific applications can be produced. Silk-based
biomaterials are at least as biocompatible in terms of inflammatory response and ability to
support cell proliferation as many materials currently in use. The degradation behaviour can be
tailored, depending on the application, from a few days to many months. These materials are
promising for use in wound healing and as tissue engineering scaffolds, particularly for the
development of skeletal tissue. Other applications, such as the use of silk for nerve regeneration,
are yet to be fully investigated.
The silks produced by silkworms and spiders have fibrous proteins that may have several
Conformations. Silks can be processed into many forms suitable for a variety of biomedical and
tissue engineering applications. They can be modified by chemical treatment or used in
combination with other materials in order to vary mechanical properties and surface chemistry.
By these means, biomaterials appropriate to specific applications can be produced. Silk-based
biomaterials are at least as biocompatible in terms of inflammatory response and ability to
support cell proliferation as many materials currently in use. The degradation behaviour can be
tailored, depending on the application, from a few days to many months. These materials are
promising for use in wound healing and as tissue engineering scaffolds, particularly for the
development of skeletal tissue. Other applications, such as the use of silk for nerve regeneration,
are yet to be fully investigated.
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