Results: Four (quasi-)
randomised trials were included, three of which reported data that could be pooled in a meta-analysis. Progressive
resistance exercise increased strength, with a standardised mean difference 0.50 (95% CI 0.05 to 0.95), and had a
clinically worthwhile effect on walking capacity, with a mean difference of 96 metres (95% CI 40 to 152) among people
with mild to moderate Parkinson’s disease. However, most physical performance outcomes did not show clinically
worthwhile improvement after progressive resistance exercise. Conclusion: This review suggests that progressive
resistance exercise can be effective and worthwhile in people with mild to moderate Parkinson’s disease, but carryover
of benefit does not occur for all measures of physical performance. The current evidence suggests that progressive
resistance training should be implemented in Parkinson’s disease rehabilitation, particularly when the aim is to improve
walking capacity.