Concentrations of prostaglandins released by
tissues maintained at 39#{176}Cwere similar to those
synthesized in vitro by bovine endometrium from
Day 17 of pregnancy (Thatcher et al., 1984). Heat
stress of endometrial tissues resulted in a marked
increase in release of PGF into culture medium,
possibly due to alterations in membranes resulting in
increased mobilization of substrates for prostaglandin
biosynthesis. The primary cellular site for the action
of heat damage on tissues is located in membranes
(Bowler et al., 1973; Hahn, 1982), causing alterations