Results: The aqueous extract exerted significant (P < 0.05) curative and prophylactic
antimalarial activities. The D/M extract exhibited significant curative (P < 0.05) but not
prophylactic antiplasmodial effect. The aqueous extract exhibited in vitro antioxidant
property with IC50's of (0.930 ± 0.021) mg/mL, (0.800 ± 0.001) mg/mL and (0.22 ± 0.05)
mg/mL in the total antioxidant capacity, reducing power and nitric oxide assays. Histological
assessment of the liver of aqueous and D/M treated animals did not reveal any
sign of toxicity.