Epidemiologic studies have identified important
risk factors for stroke, including low levels of physical
activity, high serum cholesterol levels, obesity, alcohol
use, cigarette smoking, diabetes mellitus, and hypertension
(1–3). Depression commonly occurs after a
stroke, with a prevalence as high as 30% in the first
year after the event (4). However, there has been relatively
little research on depression as a potential precursor
of stroke even though depression has been identified
as a significant risk factor for hypertension (5)
and coronary heart disease (6 –11). Depression may
also affect other stroke risk factors. Previous studies
Epidemiologic studies have identified importantrisk factors for stroke, including low levels of physicalactivity, high serum cholesterol levels, obesity, alcoholuse, cigarette smoking, diabetes mellitus, and hypertension(1–3). Depression commonly occurs after astroke, with a prevalence as high as 30% in the firstyear after the event (4). However, there has been relativelylittle research on depression as a potential precursorof stroke even though depression has been identifiedas a significant risk factor for hypertension (5)and coronary heart disease (6 –11). Depression mayalso affect other stroke risk factors. Previous studies
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