Myocardial necrosis of broiler found in all levels of Spirulina sp treatment does not show significant difference.
In treatment of 20 % Spirulina sp, necrosis does not lead to mortality.
It might be caused by the fact that the rates of TNF-like ligand 1A (TL1A) in chicken on 20 % Spirulina sp treatment were lower than those in the other traetments.
As a result, the hypovolemic shock was not as severe as that in the other treatment which experienced heavier cytokine storm.
Mortality found in treatments of 0% Spirulina sp (P0) and 10 % Spirulina sp (P1) can be due to impaired blood supply, because shock and a disorder in myocardial system can reduce blood pressure throughout the body.
The blood supply can decline or even stop and would eventually destruct the other essential organs. Anoxia experienced by the brain will cause mortality in a short time.
In this research, anoxia can be observed on wattle and comb of chicken that experienced cyanosis.
If it is related to mortality level, a dose of Spirulina sp 20% showed 0% mortality (Fig. 2) so that the dose can decrease mortality caused by Avian Influenza H5N1 virus