Sustainability concerns are that the major river basins face severe blue-water scarcity for extended periods of the year, and that water pollution levels related to nitrogen and phosphorus were found to be unsustainable in all river basins in SA. Efficient allocation and use of water is investigated by means of comparing the consumptive water footprint to global benchmark values, as well as the economic green- and blue-water productivity and the economic land productivity of the crops cultivated in SA. Furthermore, crops with specific potential for biofuel production are assessed. Lastly, recommendations to address the identified issues are given.