Alkaloids are the predominant phytochemicals found among
members of the family with 256 alkaloids characterized from
Tabernaemontana alone [4]. Tabernaemontana heyneana
Wall. is a taxon endemic to the Western Ghats of peninsular
India. The stem bark, bitter roots, flowers, and latex of
fruits are used in folk medicine to treat diseases of skin
and toothache and to reduce inflammation [5]. The indole
alkaloids and terpenoids isolated from the roots, stem bark,
fruits, and leaves possess cytotoxic, anti-implantation, and
antioxidant properties [6–8].