Liver of HFD group had numerous lipid droplets as compared
to those in the ND mice. But, AFB-treated group contains less
lipid accumulation than the high fat diet groups (Fig. 1C). The
adipocyte size of the visceral fat was significantly larger than
those of the HFD group (Fig. 1D and E). When mice were treated
with the high fat diet and AFB, the size of adipocytes was
significantly decreased compared to those of the high-fat diet
group (p < 0.05, Fig. 1E). These results indicate that AFB-induced
reduction in fat mass was partly due to a decrease in
adipocyte size.