The final rankingoftheBestKeeperalgorithmisusuallyexecutedbyassessingthe correlation coefficients of each individual gene with the geometric mean of all genes (BestKeeper Index). Higher correlation coefficients suggest more stable expression (De Spiegelaere et al., 2015). As many research demonstrated, different results could be obtained using different algorithm (Campos et al., 2015; Guo et al., 2014; Manoli et al., 2012) and none of the introduced algorithms seems to be ideal; however researchers have to choose reference gene and how to identify them (Jacob et al., 2013).