Alkaloids are alkaline compound, having one or more nitrogen atom those are part of a cyclic system. Alkaloids are widely distributed in the plant kingdom [24]. Alkaloids can be detected by extracting plant with water solvent added acid. In addition, alkaloids also can be detected by adding alkaline directly to plants sample powder, then extracted with organic solvents [24]. Alkaloids can be used as therapeutic and pharmacological agents. They have biological activities such as anti-inflammatory, antidiabetes, antioxidant and antibacterial [25-27].