An epidemiological study of endemic skeletal fluorosis has been carried out among persons 15 years old and above in an area where the drinking water contained 5 ppm F and above. In a sample of 126 persons the sequence of complaints noted was: backache, 31.74%; joint pains, 26.98%; pain in lower limbs, 17.46%; and paresthesia, 12.69%. Examination of persons with any suggestive symptoms revealed: brisk reflexes, 46.51%; kyphosis and rigidity of spine, 17.96% each; and bony exostosis, 3.46%. When three symptoms and three signs were present together, a person was diagnosed as a case of clinical skeletal fluorosis. Thus 15 persons were found to be suffering from skeletal fluorosis giving an overall prevalence of 1.13% in the study area. Urinary fluoride excretion in these individuals was higher than the fluoride level in their drinking water. This difference was found statistically significant when compared against a control group. Measurement of the Index of Independence in the Activities of Daily Living among these individuals disclosed some limitation in performing daily activity.