in cell viability and increase in cell apoptosis and caspase-3 activity, but mild reduction in the proportion of cells in S and G2/M phases, relative to the individual stimuli. n = 6; *p b 0.05 and **p b 0.01 vs. control. #p b 0.05 vs. Glu, FFA, or Hypo. Glu, glucose; Hypo, hypoxia; Com, combined stimulus; Con, control.