Obesity is considered one of the most significant factors in the development of insulin resistance, and insulin resistance can lead to type 2 diabetes. According to the World Health Organization, more than 90 percent of diabetes patients worldwide have type 2 diabetes. Being overweight or obese contributes to the development of diabetes by making cells more resistant to the effects of insulin. A weight loss of 15-20 pounds can help you decrease your risk of developing type 2 diabetes. Read: Exercising with Diabetes.