Histopathological findings. Numerous inflammatory cells including lymphocytes,
plasma cells and macrophages infiltrated the dermis, particularly the deeper dermis
of the untreated lesions on day 10 PI. Many immature fibroblasts and fewer mature
fibrocytes were also present in the dermis of the untreated lesions. The newly formed
collagen fibers of the untreated lesions were still unorganized and showed a haphazardly distributed pattern at this stage. Angiogenesis was evident in the untreated wounds (Fig.1). New blood vessels were evident in the lesions of untreated lesions at this stage and reepithelialization was not complete in the lesions of three of these animals of the untreated group on day 10 PI, however, the lesions of the remaining two rats showed a thicker epithelium and much mitotic figures. The Mean ± SD of the inflammatory cells and the blood vessels of the treated and untreated lesions are presented in Table 2. As shown in Table 2, compared to those of the control lesions, fewer lymphocytes and macrophages infi ltrated the lesions of the treated animals on day 10 PI. Greater numbers of blood
Histopathological findings. Numerous inflammatory cells including lymphocytes,plasma cells and macrophages infiltrated the dermis, particularly the deeper dermisof the untreated lesions on day 10 PI. Many immature fibroblasts and fewer maturefibrocytes were also present in the dermis of the untreated lesions. The newly formedcollagen fibers of the untreated lesions were still unorganized and showed a haphazardly distributed pattern at this stage. Angiogenesis was evident in the untreated wounds (Fig.1). New blood vessels were evident in the lesions of untreated lesions at this stage and reepithelialization was not complete in the lesions of three of these animals of the untreated group on day 10 PI, however, the lesions of the remaining two rats showed a thicker epithelium and much mitotic figures. The Mean ± SD of the inflammatory cells and the blood vessels of the treated and untreated lesions are presented in Table 2. As shown in Table 2, compared to those of the control lesions, fewer lymphocytes and macrophages infi ltrated the lesions of the treated animals on day 10 PI. Greater numbers of blood
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