The effects of aging on renal function and the lower urinary tract can be exacerbated by superimposed chronic disease, particularly diabetes mellitus. In the United States, an estimated 13% of seniors have diagnosed diabetes,[1] primarily type 2, and many more are undiagnosed. Diabetic nephropathy, a life-threatening condition, has received considerable attention. Diabetic cystopathy (DC) has received less, although it is a chronic complication that affects day-to-day life, predisposes individuals to urinary tract infections (UTIs), potentiates renal complications, and poses obstacles to optimum health. It is insidious in onset, characterized by increased length of time between voiding. Prevalence is estimated to be between 32% to 45%.[2,3]