In the case of the effervescent tablets, they absorbed water when placed into the dissolution medium, swelled
somewhat and started a one directional reaction of the effervescent agent. As by-product of this reaction CO2
bubbles were produced inside the dissolution chamber which enhanced the dissolution rate and reduced the total
dissolution time. Outer layer of the tablet become rupture by the action of effervescent agent and CO2 production
(Krögel and Bodmeier, 1999).