The 70% EtOH extracts from different cultivars of sorghum, foxtail millet and proso millet were tested for a-glucosidase inhibitory activity. Extract from sorghum significantly inhibited a-glucosidase, whereas foxtail millet and proso millet showed low inhibitory effects (Fig. 1). The 20 lg/ml extracts of foxtail millet or proso millet displayed inhibitory activities of 6–32% or 8–55%, respectively, for different cultivars (Fig. 1A and B). The percentage of inhibition of extracts from different cultivars of sorghum at 0.2,0.4, 2 and 4 lg/ml concentrations showed dose-dependent increase (Fig. 1C). For the different cultivars of sorghum, the a-glucosidase inhibitory activities were SS-1 (IC50 = 1.1 lg/ml) > SS-2
(IC50 = 1.2 lg/ml) > SS-4 (IC50 = 1.3 lg/ml) > SS-3 (IC50 = 1.4 lg/ml) > SS-5 (IC50 = 20.4 lg/ml) > SS-6 (IC50 = 102.7 lg/ml), which
indicate that extracts from sorghum cultivar, except for SS-5 and
SS-6, contained higher a-glucosidase inhibitory activities than
acarbose (IC50 = 2.1 lg/ml).
The 70% EtOH extracts from different cultivars of sorghum, foxtail millet and proso millet were tested for a-glucosidase inhibitory activity. Extract from sorghum significantly inhibited a-glucosidase, whereas foxtail millet and proso millet showed low inhibitory effects (Fig. 1). The 20 lg/ml extracts of foxtail millet or proso millet displayed inhibitory activities of 6–32% or 8–55%, respectively, for different cultivars (Fig. 1A and B). The percentage of inhibition of extracts from different cultivars of sorghum at 0.2,0.4, 2 and 4 lg/ml concentrations showed dose-dependent increase (Fig. 1C). For the different cultivars of sorghum, the a-glucosidase inhibitory activities were SS-1 (IC50 = 1.1 lg/ml) > SS-2(IC50 = 1.2 lg/ml) > SS-4 (IC50 = 1.3 lg/ml) > SS-3 (IC50 = 1.4 lg/ml) > SS-5 (IC50 = 20.4 lg/ml) > SS-6 (IC50 = 102.7 lg/ml), whichindicate that extracts from sorghum cultivar, except for SS-5 andSS-6, contained higher a-glucosidase inhibitory activities thanacarbose (IC50 = 2.1 lg/ml).
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