In 1995, at the Diagnostic Slide Session of the American
Association of Neuropathologists, Dr. William Halliday
presented a dramatic case of a 24-year-old Native
American woman with solvent vapor leukoencephalopathy
(Case 2, 1995) that showed neuropathological features
identical to Case 1 of Kornfeld et al (43). She was
a known substance abuser and had been described as often
being intoxicated and ‘‘smelling of glue.’’ Neither
detailed neurological examinations nor neuroimaging
were performed in life and she died by hanging. Despite