The in vivo study
was performed as a double blind
test by volunteers. The formulas of
the lotion are shown in Table 1. The
lotions containing 2% w/w of nonencapsulated
AL heartwood extract
and 20% w/w of encapsulated AL
heartwood extract (equivalent to
2% w/w of AL heartwood extract)
were applied twice daily on the inner
forearm of 10 female volunteers
aged between 20 and 30 years for 4
weeks. The lotion base was used as
a control. Approximately 0.1 ml of
test products was applied for each
application.
Skin color was measured by
Chromameter® CR 400 (Konica
Minolta Optics Inc.; Japan). The
individual typology angle (ITA°) was
calculated as the following equation: