Some 42.3% of control subjects were alcohol drinkers, but alcohol consumption is much more common in men (87.2% ever-drinkers among controls) than among women (15.4%). The drinkers had a 2.10-fold (95%CI=1.19-3.68, p-value=0.01) increased risk compared with never drinkers in univariate analysis (Table 2). There was no clear effect of increased frequency or duration of drinking. In addition, the alcoholic beverage with the strongest association with oral cancer was rice whisky (OR=3.8; 95%CI=1.99-7.25, p-value <0.001) when compared with never drinkers (of rice whisky). We found the risk in females, however, was 4.16 (95%CI 1.7-10.7), whereas the risk was weaker and notsignificant in males. The difference between the sexesissignificant (p-value for interaction between patient’ssexand alcohol drinking=0.002).
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