The factors underlying this state of affairs, no doubt, are numerous and intertwined. They range from cumicular priorities that have historically typified school science edu cation(AAAS 1990), to the culture of school science(e.g., Shanahan and Nieswandt 2011), to the nature of science teacher education development of teacher understandings vis-a-vis NOS and scientific inquiry(Abd-El-Khalick 2005; Abd-El-Khalick and Lederman 2000a), to challenges that often hamper systemic change in precollege science education(e.g., Vesilind and Jones 1998). The present paper focuses on a single, but rather crucial factor: namely, science teachers' knowledge domains relevant to achieving the aforementioned two goals. Toward this end, the present paper a to(a) introduce the notions of, and articulate the distinction between, teaching w and about NOS. and b) explicate science teachers' knowledge domains requisite for effective teaching with and about NOS. In this context, given the realities of school science teaching in an era o reased accountability, mostly in the form 2009. Judson 2 a foremost consideration framing my present discussion is the need to make NOS instruction an integrated and meaningful component of science teaching, which chiefly is aimed at achieving instructional outcomes related to the development of student science content knowledge and inquiry understandings and skills(Monk and osborne 1997). Approaches focused on adding modules(eg., cific or history of science units) onto already expansive science curricula a the extensive agendas of science teachers are unlikely to receive serious attention, irrespective of their perceived or actual ctiveness. As will become evident below. a framework of teaching with and about NOS is likely to be useful in addressing the well-documented difficulties associated with developing student NOS understandings and enacting science-learning environments commensurate with authentic scientific practice. In this paper, the phrase'scientific inquiry' and the term'inquiry' are meant as proxies for authentic scientific practice(Chinn and Malhorta 2002a).