HFMD is common in children and is usually caused by EVs such as Coxsackie virus and EV71. It is clinically characterised by maculopapular rash or vesicular lesions occurring on the palms, soles and other parts of the body such as the buttocks and thighs. Vesicular lesions and ulcers may also be found in the oral cavity. Sometimes patients present mainly with painful ulcers at the back of the mouth, namely herpangina, without rash on the hands or feet