Average pre-patent period of 5 days was recorded. Parasites in the blood were cleared in all
treated groups (A-D)within 48 hours post treatment (Pl). Untreated rats in group E died between
25 and 32 days post infection (PI). Relapse was not recorded in all the treated groups (A-D).
The initial reduction in PCV,Hb, TLC and increases in rectal temperature following infection
were reversed by the treatments. The rats that received drug combinations(groups B,C and D)
showed faster and higher recovery rates than the uninfected control and group A.