A number of systematic reviews about childhood obesity have been developed. However, no systematic literature review
has been conducted for youth with Down syndrome (DS). This review summarizes a large body of research on obesity and
overweight in children and adolescents with DS. Overall, findings demonstrate that youth with DS have higher rates of
overweight and obesity than youth without Down syndrome. This study also provides evidence on risk factors for obesity
in youth with DS, as well as on the effectiveness of interventions. These findings may be useful in setting a research agenda
and informing evidence-based world-wide policies for obesity prevention and control in youth with DS.