The outcomes of neonatal herpes simplex virus (HSV) disease are dependent on the extent of the disease.1 Approximately 30% of babies with disseminated disease die, but only 20% of survivors have neurologic sequelae.2 In contrast, only 6% of babies with central nervous system (CNS) disease die, but approximately 70% have permanent neurologic impairment.2 Skin, eye, and mouth disease is not associated with death, and neurologic impairment is rare with this manifestation of neonatal herpes.3