Animal modeling and grouping
Totally 98 mice were randomly divided into seven
groups by random number table method: Control (n=
14), solvent control (n=14), basic fibroblast growth factor
(BFGF) (n=14), cream of Jing Wan Hong (JWH)
(n=14), undiluted violate oil from Ainaxiang leaves
(Blumeae Balsamiferae Folium) (BB oil) (n=14), BB
oil diluted in olive oil to v/v=1/5 (BB oil1/5) (n=14),
and BB oil diluted in olive oil to v/v=1/10 (BB oil1/10)
(n=14).
Mouse wound model and drug treatments
Mice were anesthetized in advance by intraperitoneal
injection with 5% chloral hydrate (0.1 mL per 10 g).
The model skin was depilated with electric clippers.
The part of each mouse that was at the back of the
front leg, and located along the spine on the right side
of the mouse at a distance of 1.0 cm, was perforated
with a sterilized puncher. The diameter of the wound
was 1.5 cm. Then the wound was trimmed with a scalpel
to the depth of the fascia. Hemostasis was carried
out with a piece of sterile gauze. By doing these, the
mechanically induced wound animal model was
formed