- Our results indicated that the recent Thai PEDV isolates clustered in the same group were highly homologous with the Chinese strains, JS-2004-2 and LJB/03.
- They were responsible for the recent PED outbreak in Thailand and able to produce pathologic effects similar to the Chinese isolates (6).
- Notably, 08NP04, isolated 4 months after the first outbreak, had the highest identity to JS-2004-2.
- Also,08NP04 and 07NP01 (the first isolates in 2007) originated in the same geographic area.
- The Chinese-like strain of the virus might have gained entry into Thailand via unknown routes as early as December 2007.
- In addition, renderingtrucks traveling from farm to farm might have encouraged widespread transmission of the disease.
- Structural differences
- in the partial S gene could help elucidate pathogenesis and antigenic structures of the recent PEDV isolates because S glycoproteins are responsible for inducing the virus neutralizing antibodies and known to be highly conserved in PEDV strains (7).
- Continuing investigation of PEDV isolates will contribute to the prevention and control of this virus.
- Our results indicated that the recent Thai PEDV isolates clustered in the same group were highly homologous with the Chinese strains, JS-2004-2 and LJB/03. - They were responsible for the recent PED outbreak in Thailand and able to produce pathologic effects similar to the Chinese isolates (6). - Notably, 08NP04, isolated 4 months after the first outbreak, had the highest identity to JS-2004-2. - Also,08NP04 and 07NP01 (the first isolates in 2007) originated in the same geographic area. - The Chinese-like strain of the virus might have gained entry into Thailand via unknown routes as early as December 2007.- In addition, renderingtrucks traveling from farm to farm might have encouraged widespread transmission of the disease. - Structural differences- in the partial S gene could help elucidate pathogenesis and antigenic structures of the recent PEDV isolates because S glycoproteins are responsible for inducing the virus neutralizing antibodies and known to be highly conserved in PEDV strains (7).- Continuing investigation of PEDV isolates will contribute to the prevention and control of this virus.
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