Introduction
Glycation stress is one of the risk factors for aging inside
and outside of the body. Aging can most often be seen in
skin, where protein glycation and glycoxidation end product
formation cause oxidative stress that damages cell membranes.
Protein glycation occurs when blood sugar reacts with protein,
such as collagen, to form AGEs, which degrade the collagen in
skin 1-4).
Our recent research has focused on ways to inhibit AGEs
formation with the objective of treating degenerative changes,
promoting health, and mitigating the effect of lifestyle-related
disease. Several companies in the cosmetic and food industries
have funded research into glycation-inhibiting ingredients with
the goal of maintaining a youthful skin and discovering new
Anti-Aging treatments. One approach is by searching for antiglycation
and antioxidant agents from natural compounds that
inhibit AGEs formation.