Knowledge of the biomechanical behaviour of the musculoskeletal system is crucial in understanding bone diseases and in designing medical devices [26]. The skeleton normally adapts to mechanical loading, thus understanding of how bone deformation under load occurs is of interest. Several methods have been proposed for the measurement of bone deformation under load. The strain gauge (SG) was the gold standard whose electrical resistance varies proportionally to the amount of strain. A research group based in Israel used SGs for in vivo measurement of strain in human bone in six subjects during running, stationary bicycling, leg presses and stepping, using bone staples made of electrical SGs [27,28]. Recently, several researchers have studied the potential of FBG sensors for in vivo applications as a measurement tool for bone strain, concluding that FBGs have shown competitive advantages over the conventionally-used SGs. FBGs are completely made of biocompatible silicate (SiO2) glass ceramics materials [26,29] which have a smaller risk for infection, whereas the SG itself represents a foreign body implant. They can also be used in locations where the use of conventional SGs is technically inapplicable [3,26]. For example, when an SG is loaded, its electrical resistance varies proportionally to the applied strain; therefore, it cannot be used in an electromagnetic environment. Moreover, there are other distinguishing advantages of FBGs when compared to the SGs: they can easily adhere to bone and other irregular surfaces