Dandruff (“Pityriasis simplex”) is a common embarrassing disorder, affecting a large chunk of population. The yeast, Pityrosporum ovale is the contributing organism of dandruff and its lipase activity releases proinflammatory free fatty acids, causing dermal inflammation and tissue damage. Currently available treatment options have certain limitations, either due to poor efficacies or due to the compliance issues and these drugs are unable to prevent
recurrence, which is the commonest problem. This study was planned to evaluate the clinical efficacy and safety of “Anti-Dandruff Shampoo” in the management of dandruff.
This study observed a significant reduction in the mean scores of itching and white scales of dandruff. The subjective evaluation revealed a remarkable symptomatic and clinical improvement in two weeks period. The excellent antidandruff action of “Anti-Dandruff Shampoo” might have been due to the synergistic antifungal, anti-inflammatory and local immunostimulatory actions of its ingredients. Therefore, it may be concluded that, “Anti-Dandruff Shampoo” is effective and safe in the management of dandruff.