A cute kidney injury (AKI) has been reported in 5 to 7% of hospitalized patients on the basis of several single- center reports (1,2). Despite the perception that AKI is
relatively common, there is no uniform definition for AKI, and relatively few data regarding its incidence in hospitalized pa- tients are available. Moreover, the relative effects of AKI on mortality, hospital length of stay (LOS), and costs have not been well described. Most studies that have explored downstream effects of AKI have either considered AKI requiring dialysis or homogenous patient populations, such as those who were ex- posed to radiocontrast agents or undergoing cardiothoracic surgery.
In the context of a computer-based intervention in which data were collected on kidney function, severity of illness, drug prescription, and outcomes in hospitalized patients (3), we linked changes in serum creatinine (SCr) with in-hospital mor- tality, LOS, and costs. We hypothesized that relatively small changes in SCr would be common and associated with adverse outcomes, even after adjustment for severity of disea
A cute kidney injury (AKI) has been reported in 5 to 7% of hospitalized patients on the basis of several single- center reports (1,2). Despite the perception that AKI isrelatively common, there is no uniform definition for AKI, and relatively few data regarding its incidence in hospitalized pa- tients are available. Moreover, the relative effects of AKI on mortality, hospital length of stay (LOS), and costs have not been well described. Most studies that have explored downstream effects of AKI have either considered AKI requiring dialysis or homogenous patient populations, such as those who were ex- posed to radiocontrast agents or undergoing cardiothoracic surgery.In the context of a computer-based intervention in which data were collected on kidney function, severity of illness, drug prescription, and outcomes in hospitalized patients (3), we linked changes in serum creatinine (SCr) with in-hospital mor- tality, LOS, and costs. We hypothesized that relatively small changes in SCr would be common and associated with adverse outcomes, even after adjustment for severity of disea
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