In fact a specialization within mOFC may be conferred on it by the cortical route taken to it. In our study, although only activity in one cortical area, A1 of mOFC, correlated with the experience of musical and visual beauty, the path to mOFC through the two domains was different. With musical experience of beauty, auditory areas of the brain were co-active with A1 of mOFC while we could not detect any activity in the caudate nucleus. With experience of visual beauty, the caudate nucleus was very much co-active with A1 of mOFC as were the visual areas (we use the term co-active because the temporal limitations of the fMRI method do not allow us to isolate the sequence of activity in these areas). Hence, basing ourselves more on Burke’s definition of beauty given above, as one mediated by the senses, we consider that it is not activation of mOFC alone that is a determinant of beauty; it is rather the co-activation of field A1 of mOFC with the specialized sensory and perceptive area, or areas, and possibly (in the case of visual stimuli) with the caudate nucleus as well. Hence we broaden our neurobiological definition of beauty given above to include not only activation of mOFC but also its co-activation with sensory areas that feed it. The interaction between these sensory areas, and other regions such as the caudate, and A1 of mOFC, and how activity in the latter is modulated by activity in the former remains a very interesting puzzle for the future.