It is known that diet is a major contributor to NAFLD. Not only the amount of energy but also the quality of the diet plays an important role in the development and progression of NAFLD [6]. Diets rich in saturated fat, cholesterol, and low in saturated fat, fiber and antioxidant vitamins C and E have been associated with NAFLD, IR and hepatic inflammation [6]. So, the composition of Spirulina (low in saturate fat and carbohydrates, rich in polyunsaturated fatty acids, vitamins and dietary fiber) makes it attractive for the management of NAFLD.