Madison Street is a major east-west street in Chicago, Illinois. Prior to human intervention, the Chicago River emptied into Lake Michigan at the present day intersection of Madison Street and Michigan Avenue.
Per a 1908 decision by Chicago's city council, Madison serves as the north-south dividing line for Chicago's street numbering system, while State Street serves as the east-west line. At one point, the intersection between the two streets was considered the "world's busiest corner.Notable buildings located along Madison Street include the Carson, Pirie, Scott and Company Building,] Chase Tower, Three First National Plaza, the Chicago Civic Opera House, Citigroup Center and the United Center.