staying home for days or even weeks at a time due to lack of access to social situations rather than a desire to be alone;
both not contacting, and not being contacted by, any acquaintances, even peripherally; for example, never being called by anybody on the telephone and never having anyone visit one's residence;
a lack of meaningful, extended relationships, and especially close intimacy (both emotional and physical).[citation needed]
True social isolation over years and decades can be a chronic condition affecting all aspects of a person's existence. Social isolation can lead to feelings of loneliness, fear of others, or negative self-esteem.[1] Lack of consistent human contact can also cause conflict with the (peripheral) friends the socially isolated person may occasionally talk to or cause problems with family members