Design: After a 7-d cocoa-free run-in phase, 15 healthy subjects
were randomly assigned to receive for 15 d either 100 g dark chocolate
bars, which contained 500 mg polyphenols, or 90 g white
chocolate bars, which presumably contained no polyphenols. Successively,
subjects entered a further cocoa-free washout phase of 7 d
and then were crossed over to the other condition. Oral-glucosetolerance
tests were performed at the end of each period to calculate
the homeostasis model assessment of insulin resistance (HOMA-IR)
and the quantitative insulin sensitivity check index (QUICKI); blood
pressure was measured daily