Adaptive laboratory evolution works on the principle that popul ations of cells adapt to their environment
over time by natural selection . In this work, we asse ss adaptive lab oratory evolution as a tool to im prove
the perform ance of wi nemaki ng yeast strains, in order to cope with t he chal lenges of global climate
change. Specifi cally we addressed ethano l tolerance as a way to ens ure good ferme ntati on kinetics
despite increasing sug ar content in musts .