Effect of oxytetracycline and florfenicol
as growth promoters on the health status of cultured
Oreochromis niloticus
Abstract ;Several classes of antibiotics are commonly used in aquaculture; among them the most used are oxytetracycline (OTC) and florfenicol (FLO) due to their high potency against bacterial diseases. Sixty Oreochromis niloticus (20± 0.09 g) were divided into 3 groups (20 fish/group) in duplicate. Group 1 was fed a basal diet as the control group, while group 2 and 3 were fed basal diet supplemented with Oxytetracycline at 100 mg kg1 diet and Florfenicol at 5 mg kg1 body weight, respectively. After 12 weeks of feeding, group 3 showed a significant increase in the final body weight, and weight gain when compared with the control group. Group 3 did not show significant differences in immunoglobulin M (IgM) total levels with an insignificant decrease in phagocytic activity when compared to the control group. All groups showed significant increase in Lysozyme activity. Group 3 did not show significant difference in Alanine aminotransferase (ALT) activity compared to the control group, while group 2 showed the highest values of Aspartate Transaminase (AST) activity than other groups. The highest value of urea was shown in group 2, while there was a decrease in the value of creatinine in the treated groups than the control. Histopathological examination revealed pathological alterations in liver and kidney of the treated groups. After a withdrawal period of 15 days the OTC and FLO residues in O. niloticus muscle were within the permissible limit of Commission Regulation, EU (2010). In conclusion, Florfenicol at 5 mg kg1 body weight is more safe in its effect on Oreochromis niloticus. ª 2013 Production and hosting by Elsevier B.V. on behalf of National Institute of Oceanography and fisheries
Introduction
Fish aquaculture constitutes a rapidly growing industry worldwide.
This has led to a concomitant increase in aquaculture
intensity methods, which increase the susceptibility to disease
outbreaks and the necessity use of the medicated diet (Jerbi
et al., 2011). But the most dangerous is that, a large proportion
of the world’s antimicrobial industrial production is used as
Effect of oxytetracycline and florfenicol
as growth promoters on the health status of cultured
Oreochromis niloticus
Abstract ;Several classes of antibiotics are commonly used in aquaculture; among them the most used are oxytetracycline (OTC) and florfenicol (FLO) due to their high potency against bacterial diseases. Sixty Oreochromis niloticus (20± 0.09 g) were divided into 3 groups (20 fish/group) in duplicate. Group 1 was fed a basal diet as the control group, while group 2 and 3 were fed basal diet supplemented with Oxytetracycline at 100 mg kg1 diet and Florfenicol at 5 mg kg1 body weight, respectively. After 12 weeks of feeding, group 3 showed a significant increase in the final body weight, and weight gain when compared with the control group. Group 3 did not show significant differences in immunoglobulin M (IgM) total levels with an insignificant decrease in phagocytic activity when compared to the control group. All groups showed significant increase in Lysozyme activity. Group 3 did not show significant difference in Alanine aminotransferase (ALT) activity compared to the control group, while group 2 showed the highest values of Aspartate Transaminase (AST) activity than other groups. The highest value of urea was shown in group 2, while there was a decrease in the value of creatinine in the treated groups than the control. Histopathological examination revealed pathological alterations in liver and kidney of the treated groups. After a withdrawal period of 15 days the OTC and FLO residues in O. niloticus muscle were within the permissible limit of Commission Regulation, EU (2010). In conclusion, Florfenicol at 5 mg kg1 body weight is more safe in its effect on Oreochromis niloticus. ª 2013 Production and hosting by Elsevier B.V. on behalf of National Institute of Oceanography and fisheries
Introduction
Fish aquaculture constitutes a rapidly growing industry worldwide.
This has led to a concomitant increase in aquaculture
intensity methods, which increase the susceptibility to disease
outbreaks and the necessity use of the medicated diet (Jerbi
et al., 2011). But the most dangerous is that, a large proportion
of the world’s antimicrobial industrial production is used as
การแปล กรุณารอสักครู่..
