The levels of all bone metabolic markers decreased
after ACTH infusion (Fig. 3). Plasma TRAP5b activity
decreased immediately after the start of ACTH infusion
Fig. (P 0.001), but recovered by 24 h. However, it decreased
again at 36 h and thereafter. The plasma HYP
concentration also decreased up to 24 h compared with
the baseline (P 0.005). Plasma BALP activity also
decreased continuously after ACTH infusion (P
0.001), and a significant difference between groups was
not observed.