Although the exact mechanism of action against dermatophytes is unknown, luliconazole
appears to inhibit ergosterol synthesis by inhibiting the enzyme lanosterol demethylase.
Inhibition of this enzyme’s activity by azoles results in decreased amounts of ergosterol,
a constituent of fungal cell membranes, and a corresponding accumulation of lanosterol.
This will lead to a disruption of normal fungal cell membrane permeability.