The association between LP and MS was first evaluated
by Arias-Santiago et al.; however, they did not find an
increased prevalence of MS in LP patients on the basis of
NCEP ATP III criteria [13]. In a later study, Saleh et al.
reported a highly increased incidence of MS, with a rate of
77.5 % in their LP group, but they found no MS in controls
interestingly [14]. We found that the prevalence of MS in
patients with LP was 26.6 %. The MS prevalence was
higher in LP patients with mucosal involvement, with a
rate of 34.5 %. These rates were significantly higher than
in the controls, 12.7 % of whom had MS. In addition, the
rate of mucosal involvement was 90.5 % in LP patients
with MS. To the best of our knowledge, the relationship
between mucosal LP and MS has not previously been
evaluated. The prevalence of MS differs among populations,
because of differences in genetic background, dietary
habits and levels of physical activity. According to the only
study in the literature about the MS prevalence in our
region, northern Anatolia in Turkey, Erem et al. found a
rate of 26.9 % with the same criteria we used in our study While this rate is similar to the prevalence of MS in
LP patients in our study (26.6 %), LP patients with
mucosal involvement had a significantly higher MS
prevalence (34.5 %).
The association between LP and MS was first evaluatedby Arias-Santiago et al.; however, they did not find anincreased prevalence of MS in LP patients on the basis ofNCEP ATP III criteria [13]. In a later study, Saleh et al.reported a highly increased incidence of MS, with a rate of77.5 % in their LP group, but they found no MS in controlsinterestingly [14]. We found that the prevalence of MS inpatients with LP was 26.6 %. The MS prevalence washigher in LP patients with mucosal involvement, with arate of 34.5 %. These rates were significantly higher thanin the controls, 12.7 % of whom had MS. In addition, therate of mucosal involvement was 90.5 % in LP patientswith MS. To the best of our knowledge, the relationshipbetween mucosal LP and MS has not previously beenevaluated. The prevalence of MS differs among populations,because of differences in genetic background, dietaryhabits and levels of physical activity. According to the onlystudy in the literature about the MS prevalence in ourregion, northern Anatolia in Turkey, Erem et al. found arate of 26.9 % with the same criteria we used in our study While this rate is similar to the prevalence of MS inLP patients in our study (26.6 %), LP patients withmucosal involvement had a significantly higher MSprevalence (34.5 %).
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