Warehouses can be characterized in many ways, including the number of items stored, the average number of cases per pallet, throughput and inventory requirements, and demand profile, to name a few. Thus, there is no one-size-fits-all design for case-picking warehouses, and hundreds of designs are possible. Moreover, the decision variables in warehouse design are interrelated and this further complicates the design process. The purpose of this paper is to provide a set of guidelines for arriving at a “good” design configuration for a manual, case-picking warehouse.