Airborne particulate matter derived from feed yards facilitated dispersal of several veterinary antibiotics, and microbial communities containing ARG. Concentrations of several antibiotics in airborne particulate matter immediately down wind of feed yards ranged from 0.5-4.6 μg/g of particulate matter. Microbial communities of particulate matter collected down wind of feed yards were enriched with ruminant-associated taxa, and were distinct when compared to upwind PM assemblage. Furthermore, abundance of genes encoding resistance to tetracycline antibiotics was significantly greater in particulate matter collected down wind of feed yards as compared to upwind.