of TBBE was potentially attributed to quercetin and isoquerectin or the interaction between quercetin, isoquerectin and rutin. Erythromycin showed greatest antibacterial activity among all the test strains and followed by retinoic acid. The drug-free positive growth control demonstrated good growth. To check any contaminating organisms MHA plates and GAM agar plates were incubated at 37◦Cin ambient or anaerobic air for 48 h. There was no growth in any of the conditions. The cell-free negative growth control was also free of any growth.