Abstract: Ginger (Zingiber officinale) has long been used as naturopathy due to their
potential antimicrobial activity against different microbial pathogens. Moreover, in many
countries like Bangladesh, ginger is used in different boiled food preparations. This study
was conducted to determine the antimicrobial activity of soybean oil extract of dried ginger
powder, using agar diffusion assay, against 24 isolates (4 of 6 different types) of food borne
pathogens including Escherichia coli, Pseudomonas aruginosa, Staphylococcus aureus,
Vibrio cholerae, Klebsiella spp. and Salmonella spp. The present study showed the potent
antimicrobial activity of the ginger extract against the all tested bacterial pathogens. Soybean
oil extract of ginger showed highest zone of inhibition (11.67±1.53mm) against Salmonella
spp. and lowest zone of inhibition (8.0±1.73mm) against Escherichia coli. Ginger extract also
showed lower zone of inhibition (8.67±2.52mm) against Staphylococcus aureus compared to
the Gram-negative bacteria. Soybean oil extract of ginger at boiling temperature has potential
antimicrobial activity and could be used in food preparation to get the synergistic effect of
soybean and ginger.