The Maestro In-Vivo Imaging System from Cambridge Research & Instrumentation (CRi) also allows simultaneous imaging at multiple spectra, with a tunable filter that can operate at wavelengths from 500 nm to 950 nm
Skin autofluorescence is a major obstacle to imaging at visible-light wavelengths, the Maestro features analytical software that allows users to detect and eliminate autofluorescence noise, and to accurately resolve fluorescence signals from spectrally similar fluorophores
Maestro's algorithm performs spectral unmixing procedures that take into account such factors as the tissue being imaged and its depth within the animal, which can dramatically impact fluorescence detection—especially with easily scattered and absorbed photons from the visible range
"You can take a mouse that you know nothing about, stick it in the box and press a button, and it will tell you about how many spectral entities there are, calculate the spectra and unmix each signal into a different channel," says Richard Levenson, director of research for biomedical systems at CRi.
The Maestro In-Vivo Imaging System from Cambridge Research & Instrumentation (CRi) also allows simultaneous imaging at multiple spectra, with a tunable filter that can operate at wavelengths from 500 nm to 950 nm
Skin autofluorescence is a major obstacle to imaging at visible-light wavelengths, the Maestro features analytical software that allows users to detect and eliminate autofluorescence noise, and to accurately resolve fluorescence signals from spectrally similar fluorophores
Maestro's algorithm performs spectral unmixing procedures that take into account such factors as the tissue being imaged and its depth within the animal, which can dramatically impact fluorescence detection—especially with easily scattered and absorbed photons from the visible range
"You can take a mouse that you know nothing about, stick it in the box and press a button, and it will tell you about how many spectral entities there are, calculate the spectra and unmix each signal into a different channel," says Richard Levenson, director of research for biomedical systems at CRi.
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