correction. The time between PAH diagnosis and referral to our
centre (time from the first right heart catheterization diagnostic
for PAH and the first contact) was longer in patients with the
Eisenmenger Syndrome than the other subgroups (Table 1):
mean+SD was 15.9+14.3 years in Eisenmenger Syndrome,
6.2+10.0 years in PAH associated with systemic-to-pulmonary
shunts, 3.4+5.3 years in PAH associated with small defects, and
3.2+5.3 years in PAH after cardiac defect correction (P ¼
0.001). Post-tricuspid, combined, and complex defects were predominant
in patients with Eisenmenger Syndrome and in those
with PAH after cardiac defect correction. The average age at the
time of cardiac defect correction was 17.0+16.3 years
(median ¼ 11.0 years). The average time between cardiac defect