In 1988, Prof. Zografi re-viewed the critical aspects of water–solid interactions from a
fundamental, scientific perspective, highlighting the distinction between adsorption in crystalline and absorption in amorphous solids, capillary condensation, deliquescence, and for-mation of hydrates2
—physicochemical factors that continue to
challenge the development of drug products 25 years later.
In 1988, Prof. Zografi re-viewed the critical aspects of water–solid interactions from a
fundamental, scientific perspective, highlighting the distinction between adsorption in crystalline and absorption in amorphous solids, capillary condensation, deliquescence, and for-mation of hydrates2
—physicochemical factors that continue to
challenge the development of drug products 25 years later.
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